Imaging techniques in parathyroid surgery for primary hyperparathyroidism

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Re-explorative Parathyroid Surgery for Persistent and Recurrent Primary Hyperparathyroidism

Primary hyperparathyroidism (HPT) is treated by parathyroidectomy. Excision of abnormal parathyroid tissue is curative in the majority of cases. Postoperative persistent or recurrent HPT has been reported up to 30%. The purpose of this study was to evaluate the role of imaging techniques and determine the efficacy of reexplorative surgery. A total of 306 patients underwent parathyroidectomy bet...

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Imaging of the parathyroid glands in primary hyperparathyroidism.

Primary hyperparathyroidism (PHPT) is one of the most frequent endocrine diseases worldwide. Surgery is the only potentially curable option for patients with this disorder, even though in asymptomatic patients 50 years of age or older without end organ complications, a conservative treatment may be a possible alternative. Bilateral neck exploration under general anaesthesia has been the standar...

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Mediastinal parathyroid adenoma causing primary hyperparathyroidism.

An ectopically placed parathyroid adenoma in the anterior mediastinum is a rare cause of persistent or recurrent primary hyperparathyroidism (PHPT) and is recognized as an important cause of failed primary neck exploration. We encountered 3 such cases amongst 70 surgically treated patients with PHPT (4.3%) over a 20-year period. In 2 cases, the offending adenoma could be removed at first explor...

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Parathyroid hormone-related peptide and primary hyperparathyroidism.

The parathyroid hormone-related peptide (PTHrP) has been shown to be the major pathogenic factor to humoral hypercalcemia of malignancy (HHM). The presence of PTHrP in many normal tissues and in normal or abnormal parathyroids has been described in literature and its role has been investigated. PTHrP release from parathyroid cells into the extracellular space has been demonstrated to depend on ...

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Primary hyperparathyroidism due to parathyroid adenoma.

OBJECTIVE To evaluate the clinical characteristics and outcome of patients with parathyroid adenoma. METHODS We diagnosed and operated 54 patients with primary hyperparathyroidism in the Faculty of Medicine, Gazi University, Turkey from January 2000 to December 2004. In this study, 52 (96.2%) of these patients who had parathyroid adenoma were retrospectively evaluated. RESULTS There were 46...

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ژورنال

عنوان ژورنال: American Journal of Otolaryngology

سال: 2012

ISSN: 0196-0709

DOI: 10.1016/j.amjoto.2011.10.010